So many infections today are the reason for the death of people as they develop due to extremely resistant bacteria. This is a new research area, and much research projects are still in the infancy or trial stages; however, expectations are high, and we would potentially do away with genetic diseases soon enough. Gene therapy can act as a plug by blocking by passing down of such hazardous defects. Why is Bioinformatics important in Genetic Research? But now gene therapy has somehow alleviated the hazards of these disorders. We can be confident that all the unborn babies will be delivered safely and grow to their prime. The pros and cons of gene therapy show us that there are some uncomfortable questions that need to be answered as this technology progresses. By replacing a defective gene with a functional gene in a disease like cystic fibrosis, there are limited chances of remission, and this is usually a one-off treatment that will see you symptom-free for life. There is no guarantee that gene therapy will fulfill its expectations to treat explicit disorders, performing gene adjustments could create new defects for future generations without realizing it; thus it can be a double-edged sword. Developed in 1972, gene therapy can be of two type; somatic gene therapy and germline gene therapy. Such a fee may not be affordable to many, and this will create socioeconomic segregation as the rich will be disease-free while the poor remain to bear the burden of such illness. *, Cite this article as: "Top 20 Gene Therapy Pros and Cons," in. Gene therapy promises much potential in the medical field ranging from relieving the pill burden to modifying phenotypes in cosmetology. Some of the congenital abnormalities manifest quite early, and there are minimal hopes for survival in these children, this causes much pain to their families because management option is limited and there is very little at their disposal to modify such conditions. One of the greatest hindrance to the advancement of gene therapy is the opposition on the basis that it can open room for unethical science which may be demeaning to the human race. 3. The massive ongoing research will leverage the concerns and provide a technological-based method with a high certainty of results. Critics have their say and look at the two sides of the story will lead us to weigh risk: benefit ration. All Rights Reserved. Gene therapy can provide a chance of treatment of even those diseases that currently don’t have a treatment protocol. Some of the notable disadvantages of gene therapy include; As at now, gene therapy is at the developmental stages, and most experiments are done on the animals with the hope that success will be reflected in humans. Gene therapy which today is considered ultimate treatment solution might face such outcomes in future. Copyright © 1999-2020 BioExplorer.Net. Not only does gene therapy focus on diseases. Posted by Biolyse | Nov 3, 2018 | Gene Therapy | 0 |. Ineffective Approach to Medical Science, https://www.bioexplorer.net/gene-therapy-pros-cons.html/, Top 10 Best Neurosurgery Schools in America, Top 25 Most Recent Genetic Discoveries in 2018, Top 10 BEST Colleges For Nutrition and Dietetics, Best Colleges For Environmental Engineering, World’s 25 Most Pretty Purple Flowers (), The 25 Most Notable Biology Discoveries of All Times. When you remove a gene predisposing one to breast cancer they won’t transfer the defective genes to their offspring but the new functional gene. Genetically disordered persons live a very miserable life, and most of them cannot make up for long so gene therapy can help them to live a healthy and long life. Genes are microstructures; anything can go wrong during a treatment method. Some of them are listed below: Here are some of the pros or advantages of gene augmentation therapy: Rare genetic disorders today affect about 10% of the population in general. Critics have their say and look at the two sides of the story will lead us to weigh risk: benefit ration. Gene therapy may yield patient to the point on which he has to go on with the more complicated problem as compared to what he was facing originally. Using an adjusted and modified genetic therapy method called “CRISPR“, proper alterations to fertility have occurred in specific mice species. If a person succeeds only because of attained/gained intelligence or strength, this surely is a matter of sheer injustice with other participants. There may also be unforeseen side effects that could cause more harm than good as we work to treat some of the most devastating conditions that humans experience right now. Although gene therapy has a potential for treating several ailments and improving life, this is a relatively new technique and involve several safety concerns thus it should be carefully embraced. Some of the initially incurable diseases can be managed and possibly eliminated when we involve gene therapy. Gene therapy pros and cons can be quite decisive on whether or not we should embrace gene therapy. Besides, gene therapy promises a cure for the chronic illnesses that are currently incurable for example cancer that causes agonizing pain in many. Conditions that may make life unlimited such as infertility are also accounted for, and it is projected that soon enough gene therapy should activate reproductive genes and allow you to have children. Promises a cure for the chronic illnesses that are currently incurable for example cancer causes! Listed cons, '' in cause in deaths of newborn infants probably in... Significant changes in lifestyle and with some aid from medications metabolic pathways, which is unable afford! Due to misalignment, missing genes or excess of a gene failure of story... 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